2024-2025 Publications
1.) Bergstrom AR, Glimm MG, Houske EA, Cooper G, Viles E, Chapman M, Bourekis K, Welhaven
HD, Brahmachary PP, Hahn AK, June RK (2025 Mar). Metabolic Profiles of Encapsulated
Chondrocytes Exposed to Short-Term Simulated Microgravity. Annals of biomedical engineering,
53(3), 785-797. . ID: 39695002.
2.) Welhaven HD, Welfley AH, Brahmachary PP, Smith DF, Bothner B, June RK (2025 Feb 7).
Tissue-specific and spatially dependent metabolic signatures perturbed by injury in
skeletally mature male and female mice. bioRxiv : the preprint server for biology,
(), . . ID: 39975211.
3.) Jackson OD, Reyes A, Stein CD, Larson NG, Andrews CT, Neufeldt SR (2025 Jan 29). C2-Selective
Palladium-Catalyzed C-S Cross-Coupling of 2,4-Dihalopyrimidines. Journal of the American
Chemical Society, 147(4), 3017-3022. . ID: 39829005.
4.) Cooper G, North R, Hunt-Smith T, Larson J, Rennie M, Bailey ML, Scarlata S, Merzdorf
CS, Bothner B (2025 Jan 26). Persistent Metabolic Changes Are Induced by 24 h Low-Dose
Lead (Pb) Exposure in Zebrafish Embryos. International journal of molecular sciences,
26(3), . . ID: 39940818.
5.) Brahmachary PP, Erdogan AE, Myers EP, June RK (2025 Jan 23). Metabolomic Profiling
and Characterization of a Novel 3D Culture System for Studying Chondrocyte Mechanotransduction.
bioRxiv : the preprint server for biology, (), . . ID: 38915493.
6.) Larson J, Tokmina-Lukaszewska M, Malone J, Hasenoehrl EJ, Kelly W, Fang X, White A,
Patterson A, Bothner B (2025 Jan 8). The Use of Dansyl Chloride to Probe Protein Structure
and Dynamics. International journal of molecular sciences, 26(2), . . ID: 39859172.
7.) Loveday EK, Welhaven H, Erdogan AE, Hain KS, Domanico LF, Chang CB, June RK, Taylor
MP (2025). Starve a cold or feed a fever? Identifying cellular metabolic changes following
infection and exposure to SARS-CoV-2. PloS one, 20(2), e0305065. . ID: 39937842.
8.) Hager MS, Cook JP, Bothner B, Weaver DK (2025). Untargeted metabolomic and transcriptomic
analysis in spring and durum wheat reveals potential mechanisms associated with the
early stem solidness phenotype and resistance to wheat stem sawfly. Frontiers in plant
science, 16(), 1497732. . ID: 40046948.
9.) Welhaven HD, Welfley AH, Bothner B, Messier SP, Loeser RF, June RK (2024 Dec 20).
The metabolome of male and female individuals with knee osteoarthritis is influenced
by 18-months of weight loss intervention: the IDEA trial. BMC musculoskeletal disorders,
25(1), 1057. . ID: 39707277.
10.) Deveryshetty J, Mistry A, Pangeni S, Ghoneim M, Tokmina-Lukaszewska M, Kaushik V,
Taddei A, Ha T, Bothner B, Antony E (2024 Nov 7). Rad52 sorts and stacks Rad51 at
the DNA junction to promote homologous recombination. bioRxiv : the preprint server
for biology, (), . . ID: 39574592.
11.) Kant R, Lee LS, Patterson A, Gibes N, Venkatakrishnan B, Zlotnick A, Bothner B (2024
Oct 23). Small Molecule Assembly Agonist Alters the Dynamics of Hepatitis B Virus
Core Protein Dimer and Capsid. Journal of the American Chemical Society, 146(42),
28856-28865. . ID: 39382517.
12.) Pincus SH, Cole FM, Ober K, Tokmina-Lukaszewska M, Marcotte T, Kovacs EW, Zhu T, Khasanov
A, Copié V, Peters T (2024 Oct 22). Conjugation of anti-HIV gp41 monoclonal antibody
to a drug capable of targeting resting lymphocytes produces an effective cytotoxic
anti-HIV immunoconjugate. Journal of virology, 98(10), e0064724. . ID: 39283123.
13.) Spears M, Cooper G, Sather B, Bailey M, Boles JA, Bothner B, Miles MP (2024 Oct 3).
Comparative Impact of Organic Grass-Fed and Conventional Cattle-Feeding Systems on
Beef and Human Postprandial Metabolomics-A Randomized Clinical Trial. Metabolites,
14(10), . . ID: 39452914.
14.) Larson J, Sather B, Wang L, Westrum J, Tokmina-Lukaszewska M, Pauley J, Copié V, McDermott
TR, Bothner B (2024 Sep 2). Metalloproteomics Reveals Multi-Level Stress Response
in Escherichia coli When Exposed to Arsenite. International journal of molecular sciences,
25(17), . . ID: 39273475.
15.) Welhaven HD, Welfley AH, Pershad P, Satalich J, O (2024 Sep). Metabolic phenotypes
reflect patient sex and injury status: A cross-sectional analysis of human synovial
fluid. Osteoarthritis and cartilage, 32(9), 1074-1083. . ID: 37716406.
16.) Chamberlin ML, Peach JT, Wilson SMG, Miller ZT, Bothner B, Walk ST, Yeoman CJ, Miles
MP (2024 Aug 30). Polyphenol-Rich Aronia melanocarpa Fruit Beneficially Impact Cholesterol,
Glucose, and Serum and Gut Metabolites: A Randomized Clinical Trial. Foods (Basel,
Switzerland), 13(17), . . ID: 39272533.
17.) Larson J, Tokmina-Lukaszewska M, Payne D, Spietz RL, Fausset H, Alam MG, Brekke BK,
Pauley J, Hasenoehrl EJ, Shepard EM, Boyd ES, Bothner B (2024 Aug 21). Impact of mineral
and non-mineral sources of iron and sulfur on the metalloproteome of Methanosarcina
barkeri. Applied and environmental microbiology, 90(8), e0051624. . ID: 39023267.
18.) Costello SM, Schultz A, Smith D, Horan D, Chaverra M, Tripet B, George L, Bothner
B, Lefcort F, Copié V (2024 Jul 31). Metabolic Deficits in the Retina of a Familial
Dysautonomia Mouse Model. Metabolites, 14(8), . . ID: 39195519.
19.) Kania MJ, Reyes A, Neufeldt SR (2024 Jul 17). Oxidative Addition of (Hetero)aryl (Pseudo)halides
at Palladium(0): Origin and Significance of Divergent Mechanisms. Journal of the American
Chemical Society, 146(28), 19249-19260. doi: 10.1021/jacs.4c04496. ID: 38959060.
20.) Larson NG, Norman JP, Neufeldt SR (2024 May 3). Mechanistic Origin of Ligand Effects
on Exhaustive Functionalization During Pd-Catalyzed Cross-Coupling of Dihaloarenes.
ACS catalysis, 14(9), 7127-7135. . ID: 38911468.
21.) Welhaven HD, Viles E, Starke J, Wallace C, Bothner B, June RK, Hahn AK (2024 Apr 9).
Metabolomic profiles of cartilage and bone reflect tissue type, radiography-confirmed
osteoarthritis, and spatial location within the joint. Biochemical and biophysical
research communications, 703(), 149683. doi: 10.1016/j.bbrc.2024.149683. ID: 38373382.
22.) Welhaven HD, Welfley AH, Brahmachary P, Bergstrom AR, Houske E, Glimm M, Bothner B,
Hahn AK, June RK (2024 Mar 25). Metabolomic Profiles and Pathways in Osteoarthritic
Human Cartilage: A Comparative Analysis with Healthy Cartilage. Metabolites, 14(4),
. . ID: 38668311.
23.) Welhaven HD, Wefley AH, Bothner B, Messier SP, Loeser RF, June RK (2024 Feb 16). The
metabolome of individuals with knee osteoarthritis is influenced by 18-months of an
exercise and weight loss intervention and sex: the IDEA trial. bioRxiv : the preprint
server for biology, (), . . ID: 38405821.
24.) Fausset H, Spietz RL, Cox S, Cooper G, Spurzem S, Tokmina-Lukaszewska M, DuBois J,
Broderick JB, Shepard EM, Boyd ES, Bothner B (2024 Feb 6). A shift between mineral
and nonmineral sources of iron and sulfur causes proteome-wide changes in Methanosarcina
barkeri. Microbiology spectrum, 12(2), e0041823. . ID: 38179920.
